Can our microbiome tells us much about ourselves?

Academic institutions, including University of Colorado and the University of Chicago, have already started focusing on microbiome research. It is very interesting to me when you come to realize that each human being is essentially a walking Petri dish. There is more bacteria in your body than the cells you have. Think about that – think about how much bacteria in your gut may possibly control your metabolism, your thoughts, or maybe even your life.

Microbiome startups, like ClostraBio, at the University of Chicago, spearheaded by immunologists and biomedical engineer, are looking into altering microbiome to cure food allergy. This is not it – microbiome may even have a bigger role than food allergy. I just came back from the second last day of ASCO – American Society of Clinical Oncology 2017. Microbiome diversity apparently is been linked to how well you will respond to immune therapy (PD-1 therapy, like Keytruda or Opdivo. Researchers found that responders to the therapy have different microbiome make-up than those who don’t respond. 

The story gets even more interesting. When they transplanted fecal matter (microbiome) from responders or non responders to germ free mice, they found that mice respond differently when they are xenografted with tumor cells.

They are now exploring the application of fecal transplantation and the use of probiotic in cancer treatment. 

Anyway, be aware of the power of these micro organisms in your gut!

MATTER/ CHIentist Workshop on 3/7 Recruiting Now!

In partnership with MATTER, we will be hosting a workshop for the annual Midwest University Healthcare Technology Showcase (MUHTS). MUHTS is a technology showcase of academic innovations for pharmaceutical and medical device companies.

The workshop will be held on March 7 from 3- 7 pm. It will feature an introduction to MATTER and MUHTS by Dr. Maryam Saleh (VP of Programs at MATTER); a crash course on how to build an effective technology summaries for executives, a collaborative work session of MBAs and PhDs to work on summaries received from universities across the US, and followed by a networking event.

Join us at the workshop to be a part of the exciting process in academic ventures!

To sign up: Please visit:

Protocome idea

A while ago,  I came up with the idea of protocome.  An startup that allows people,  specifically scientists,  to share their protocol online.  Now you probably may ask why do we need that?  

If you go to any publications now,  chances are you will see a experiments section or the experimental procedure session. At this time,  there is no standardized method to present this section.  And worse is that some authors may give out as little as information as possible, so that it can be their little secret sauce (though you can probably just ask them directly for the protocol in details,  but that’s so inefficient). 

Getting back to this point,  protocol storage and sharing is a must do in the scientific community.  Yet this step is not standardized and is running very inefficiently right now. 

How can we solve this?  I think the best way is to mine all the open Access protocols out there.  For example,  plos one lets you mine through their data.  Then sort it out by figuring out the most common phrases for each identical type of experiments. Then that will be the gold standard

I envision us just citing the experiments in the future like, protocome, standard 1234, adjustment : sodium chloride (1ug).

Is this too fast fetched? I hope not!